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Updated: Jul 5, 2025

Platelet Adhesion and Aggregation Under Flow using Microfluidic Flow Cells
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GDF-15通过GFRAL/RET信号复合体抑制ADP诱导的人类血小板聚合

Baikang Xie1,2,3, Wenjing Tang1,2,3, Shuang Wen4

  • 1Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.

Biomolecules
|January 23, 2024
PubMed
概括

增长分化因子-15 (GDF-15) 通过结合GFRAL和调节AKT和ERK通路来抑制腺二酸盐 (ADP) 诱导的血小板激活. 这揭示了GDF-15在心血管健康中的新机制.

关键词:
细胞外信号调节的激酶.质细胞系衍生的神经营养因子家族受体α类.增长差异化因子-15-15血小板 血小板 血小板是什么?蛋白质激酶B的蛋白质激酶B.

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