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Updated: Jul 5, 2025

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分子建模研究,以证明新型化合物的结合假设对抗多药耐药蛋白ABCB1的结合假设

Yasmeen Cheema1, Kenneth J Linton2, Ishrat Jabeen1

  • 1School of Interdisciplinary Engineering & Sciences (SINES), National University of Science and Technology, Sector H-12, Islamabad 44000, Pakistan.

Biomolecules
|January 23, 2024
PubMed
概括

研究人员发现了新型化合物,可以强烈抑制ABCB1 (P-糖蛋白),这是多药耐药性的关键因素. 分子动力学模拟揭示了这些抑制剂如何改变传送器.

关键词:
在ABCB1中,ABCB1是ABCB1.模拟MD的模拟方法连接体ABCB1 相互作用分子对接模拟分子对接模拟

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