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Updated: Jul 5, 2025

LDL Cholesterol Uptake Assay Using Live Cell Imaging Analysis with Cell Health Monitoring
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SLCO1B1 基因变异对儿科高胆固醇血症中阿托瓦斯塔丁全身暴露的影响

Jonathan B Wagner1,2,3, Susan Abdel-Rahman2,3, Geetha Raghuveer1,3

  • 1Ward Family Heart Center, Children's Mercy, Kansas City, MO 64108, USA.

Genes
|January 23, 2024
PubMed
概括

在患有高胆固醇的儿童中,SLCO1B1基因变异显著影响阿托瓦斯塔丁水平. 增加的体重指数也会影响药物暴露,需要个性化剂量以防止毒性.

关键词:
胆固醇 胆固醇 胆固醇 是一种脂质 脂质 脂质 是一种儿科 儿科 儿科 儿科药物基因组学 药物基因组学药物动力学 药物动力学类药物 类药物 类药物

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