低剂量对电离辐射和心血管影响的职业暴露:叙述性审查
Guglielmo Manenti1, Luca Coppeta2, Ivan Valentinov Kirev1
1Department of Diagnostic and Interventional Radiology, Molecular Imaging and Radiotherapy, PTV Foundation, University of Rome Tor Vergata, 00133 Rome, Italy.
Healthcare (Basel, Switzerland)
|January 23, 2024
概括
低剂量的电离辐射可能会增加心血管疾病 (CVD) 的风险,挑战历史观点. 需要进一步的研究来澄清这种复杂的关系,特别是在0.5 Gy以下.
科学领域:
- 辐射生物学 辐射生物学
- 心血管流行病学心血管流行病学
- 职业健康 职业健康 职业健康 职业健康
背景情况:
- 从历史上看,低剂量的电离辐射不被认为是非癌症疾病的重大风险.
- 新出现的证据表明,即使在比以前假设的辐射剂量更低的情况下,潜在的心血管疾病 (CVD) 风险也存在.
研究的目的:
- 审查和报告研究低剂量电离辐射暴露在职业暴露的个体中的心血管疾病风险的研究.
主要方法:
- 一项系统的数据库搜索发现了1151项研究.
- 27篇代表性文章被选为本次综述.
主要成果:
- 已发表的研究表明,电离辐射暴露与心血管问题之间存在积极的关联,包括皮肤微循环损伤,缺血性心脏病和脑血管疾病.
- 低于0.5 Gy的剂量风险关系由于有限的统计能力而仍然没有确定性.
结论:
- 电离辐射暴露和心血管疾病之间的关系是复杂的,需要进一步的全面研究.
- 潜在的无值剂量风险关系可能会显著改变目前的低剂量辐射健康风险评估.
相关概念视频
Biological Effects of Radiation
15.5K
All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...
15.5K
Imaging Studies for Cardiovascular System III: X-Ray
188
The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
188
Psychoneuroimmunology: Cardiovascular Disease
31
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...
31
Positron Emission Tomography
4.2K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
4.2K
Radiological Investigation III: Pulmonary Angiogram and PET Scan
93
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
93
Types of Toxins
1.7K
Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
1.7K


