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Updated: Jul 5, 2025

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单细胞DNA测序和免疫表型分析,以追踪急性髓性白血病患者的克隆进化

María García-Álvarez1, Ana Yeguas2, Cristina Jiménez1

  • 1Hematology Department, University Hospital of Salamanca (HUS/IBSAL), CIBERONC and Cancer Research Institute of Salamanca-IBMCC (USAL-CSIC), 37007 Salamanca, Spain.

Biomedicines
|January 23, 2024
PubMed
概括

单细胞测序揭示了急性髓性白血病 (AML) 中的一个小FLT3-ITD克隆,在治疗后扩大,导致复发. 这凸显了跟踪AML治疗耐药性的小克隆的重要性.

关键词:
在FLT3-ITDD中使用.急性骨髓性白血病 (AML) 是一种急性骨髓性白血病.吉尔特里尼布和克隆进化免疫类型 免疫类型中间质尿素 (Midostaurin) 是一种神经元.这是下一代测序.一个单细胞DNA测序.

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