多发性硬化症中的头痛和其他疼痛综合征:叙述性综述
Carmen Adella Sîrbu1,2,3, Andreea Ruxandra Rotaru2, Florina Anca Antochi4
1Clinical Neurosciences Department, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Life (Basel, Switzerland)
|January 23, 2024
概括
头痛,包括偏头痛,在多发性硬化症 (MS) 患者中越来越常见. 本综述探讨了MS和头痛之间的联系,将其与偏头痛区分开来,并考虑了治疗的影响.
科学领域:
- 神经学 神经学
- 神经免疫学 神经免疫学
背景情况:
- 多发性硬化症 (MS) 是一种具有重大社会经济影响的慢性神经疾病.
- 在MS患者中注意到头痛的发病率增加,如偏头痛和紧张性头痛.
- 头痛通常被忽视为MS症状,尽管可能表明疾病或治疗副作用.
研究的目的:
- 评估MS相关头痛的特征,包括频率,与MS发作的相关性以及疾病修饰疗法 (DMT) 的影响.
- 为了区分多发性硬化症脱髓化病变和初级头痛成像发现.
- 探索MS和头痛之间潜在的共同触发因素或病理生理机制.
主要方法:
- 文献综述侧重于流行病学数据,临床观察和神经成像研究.
- 对诊断挑战的分析,特别是区分MS发作和带有光环的偏头痛.
- 检查头痛发作/恶化与DMT启动和潜在的改善与某些DMT.
主要成果:
- 头痛是多发性硬化症中常见的,但往往被忽视的症状,影响生活质量.
- 由于神经系统症状重叠,MS发作和带有光环的偏头痛之间的差异诊断至关重要.
- 对MS的治疗干预可以影响头痛的表现,一些DMT可能会改善头痛症状.
结论:
- 需要进一步的研究来阐明MS和头痛之间的病理生理联系.
- 了解MS,头痛及其治疗之间的关系对于全面的患者护理至关重要.
- 区分MS病变的成像特征与初级头痛的成像特征对于准确诊断至关重要.
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