含有乳腺素的蛋白9调节信号通路,并重新编程人类子宫纤维细胞的表观基因组

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Establishing 3D Endometrial Organoids from the Mouse Uterus
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Establishing 3D Endometrial Organoids from the Mouse Uterus

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Qiwei Yang1, Somayeh Vafaei1, Ali Falahati2

  • 1Department of Obstetrics and Gynecology, University of Chicago, 5841 S. Maryland Ave., Chicago, IL 60637, USA.

International journal of molecular sciences
|January 23, 2024
PubMed
概括

含基蛋白9 (BRD9) 在子宫纤维瘤 (UFs) 中被上调. 抑制BRD9抑制了UF生长,减少了细胞外基质沉积,并重新编程了表观基因组,这表明了对UFs的新型非激素疗法.

关键词:
这就是BRD9的原因.在I-BRD9中,通过RNA甲基化.灭症 (apoptosis) 是一种死亡的过程.细胞的增殖细胞的增殖.染色体重塑 染色体重塑的方法显基因组是一个表观基因组.副本转录组 (epitranscriptome) 是一个副本转录组.细胞外矩阵是细胞外矩阵.m6A 调节器 调节器转录组 (transcriptome) 是一个转录组.在子宫的leiomyomaoma.

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