乳腺癌中的瘤微环境和免疫反应
Behjatolah Monzavi-Karbassi1, Thomas Kelly1, Steven R Post1
1Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
International journal of molecular sciences
|January 23, 2024
概括
瘤微环境极大地影响癌症的进展和治疗结果. 了解这些相互作用是改善患者预后的关键.
科学领域:
- 在瘤学瘤学.
- 癌症生物学 癌症生物学
- 瘤微环境研究 研究
背景情况:
- 瘤微环境 (TME) 包括癌细胞,层细胞,免疫细胞和细胞外基质.
- 在TME内的复杂的细胞和分子交叉声调决定了瘤的行为.
相关概念视频
02:17The Tumor Microenvironment
6.6K
Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
6.6K
01:27Tumor Immunotherapy
527
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
527