异形慢性过渡性便秘:病理生理学,诊断和管理
Luke J Vlismas1,2, William Wu1,3, Vincent Ho1,3
1Deptartment of Gastroenterology, Campbelltown Hospital, Campbelltown, NSW 2560, Australia.
缓慢过渡便秘 (STC) 是一种结肠神经肌肉疾病,呈现耐火性症状,影响生活质量. 管理涉及生活方式的改变,药物治疗,以及严重病例的潜在手术.
科学领域:
- 胃肠病学 胃肠病学
- 结肠直肠手术 结肠直肠手术
- 身体生理学 身体生理学
背景情况:
- 缓慢过渡性便秘 (STC) 影响2~4%的人口,导致严重的心理社会压力和高医疗费用.
- STC的特征是结肠不运动,一种神经肌肉疾病.
- 它是最不常见但最耐火的慢性便秘表型.
研究的目的:
- 提供STC病理生理学,诊断和管理的概述.
- 突出诊断STC的挑战,并将其与其他类型的便秘区分开来.
- 审查STC各种治疗方案的有效性.
主要方法:
- 审查关于STC病理生理学,诊断和治疗的现有文献.
- 讨论诊断标准,包括结肠过境时间评估.
- 对管理策略的分析,从生活方式的改变到手术干预.
主要成果:
- STC病理生理学涉及减少结肠收缩,延迟排空和改变神经递质水平.
- 诊断需要排除其他类型的便秘,并评估结肠过境时间.
- 催化剂是耐火病例的支柱,手术为医学上难以治疗的STC提供了一个选择.
结论:
- STC是一种具有重大疾病负担的具有挑战性的疾病.
- 对临床医生来说,结构化的诊断和管理方法至关重要.
- 虽然存在各种疗法,但它们的有效性各不相同,耐火病例可能需要手术干预.
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