在心力衰竭患者中,septal缩的预后影响,心脏衰竭患者的喷射分数略有减少
Noah Abel1, Tobias Schupp1, Mohammad Abumayyaleh1
1Department of Cardiology, Angiology, Haemostaseology and Medical Intensive Care, University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.
Journal of clinical medicine
|January 23, 2024
概括
阴道缩,心力衰竭中心脏重塑的指标轻微减少喷射率 (HFmrEF),预测住院治疗恶化的HF,但不是所有原因的死亡率. 这一发现突显了它对与HF相关的再住院治疗的预后价值.
科学领域:
- 心脏病学 心脏病学
- 心血管成像 - 心血管成像
- 心脏衰竭研究研究
背景情况:
- 心脏重塑是心力衰竭 (HF) 的关键特征,表明疾病进展.
- 隔膜缩,通过腹腔间隔膜末端透气 (IVSd) 测量,是重塑的常见方面.
- 隔膜缩在轻微减少喷射分数 (HFmrEF) 的心力衰竭中的预后意义仍然未得到充分研究.
研究的目的:
- 评估患有HFmrEF的患者中隔膜缩的预后价值.
- 评估隔膜缩和全因死亡率以及与HF相关的住院病例之间的关联.
主要方法:
- 从2016-2022年对1881名住院的HFmrEF患者 (LVEF 41-49%) 的回顾性分析.
- 被定义为IVSd>12毫米的 Septal 缩.
- 统计分析包括多变量调整和倾向得分匹配.
主要成果:
- 在34%的HFmrEF患者中存在 Septal 缩.
- 在30个月后,隔膜缩和全因死亡率之间没有发现显著的关联.
- 隔膜缩独立地与由于30个月后HF恶化而增加住院风险有关.
结论:
- 在HFmrEF患者中, Septal 缩并不是所有原因死亡率的预测因素.
- 隔膜缩是该人群中长期HF相关再住院的独立预测因素.
- 对隔膜缩的心声学评估可能有助于对HFmrEF患者的风险分层.
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