在COVID-19的重症患者中评估流体状况:回顾性队列研究
Nadia Rodríguez-Moguel1, Ivan Armando Osuna-Padilla2, Karolina Bozena Piekarska3
1Departamento de Investigación en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias "Ismael Cosío Villegas", Mexico City 14080, Mexico.
Journal of clinical medicine
|January 23, 2024
概括
在重症COVID-19患者中评估液体状况具有挑战性. 生物电阻分析 (BIA) 确定了过度水分,这是死亡率的预测因素,与其他方法不同.
科学领域:
- 关键护理医学 关键护理医学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 传染性疾病 传染性疾病
背景情况:
- 流体状况 (FS) 管理在重症COVID-19患者中很复杂.
- 准确的FS评估对于预测结果至关重要.
研究的目的:
- 为了比较流体平衡 (CFB),生物电阻分析 (BIA) 和超声波 (VExUS) 以预测严重的COVID-19死亡率.
- 为了确定与死亡率相关的可靠FS参数.
主要方法:
- 79名严重的COVID-19患者的回顾性审查.
- 收集了CFB,BIA和VexUS的入院和每周的数据.
- 分析FS参数用于死亡率预测.
主要成果:
- 只有BIA发现了与死亡率相关的FS异常.
- 细胞外水/总体水比>0.394 (过水) 预测死亡率 (AUC=0.78).
- 过多水分增加了死亡风险 (OR 6.2) 和缩短了生存时间 (HR 2.82).
结论:
- BIA是评估重症COVID-19患者流体状况的宝贵工具.
- 由BIA确定的过度水分是死亡率的独立预测因素.
- 过度水分的早期检测可以指导干预措施以改善结果.
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