一项关于Lathyrus tuberosus L.的综合研究:关于植物化学成分,抗菌活性,抗氧化能力,细胞毒性和细胞迁移效应的见解
Rita Jakabfi-Csepregi1,2, Ágnes Alberti3, Csenge Anna Felegyi-Tóth3
1Department of Laboratory Medicine, Medical School, University of Pécs, Ifjúság u. 13, HU-7624 Pécs, Hungary.
Plants (Basel, Switzerland)
|January 23, 2024
概括
来自Lathyrus tuberosus叶的化合物具有显著的抗氧化和抗菌特性. 这些发现表明,有可能从这种植物来源开发新的营养药.
科学领域:
- 植物化学 植物化学
- 药理学 药理学是指药理学的学科.
- 民族医学 民族医学
背景情况:
- 传统上,Lathyrus tuberosus的叶子在特兰西瓦尼亚民族医学中被使用.
- 这些叶子的植物化学特征和生物活性需要进行全面的研究.
研究的目的:
- 研究来自Lathyrus tuberosus叶的化合物的体外抗氧化,抗微生物,细胞毒性和细胞迁移效应.
- 为了描述Lathyrus tuberosus叶子提取物的多和单构成物.
主要方法:
- 超高性能液体染色学-并联质谱学 (UHPLC-MS/MS) 用于化合物识别.
- 微稀释试验用于抗微生物活性测定.
- 无细胞和基于细胞的测定用于抗氧化能力评估.
- 在实验室中对3T3纤维细胞和HaCaT角质细胞进行细胞毒性测定.
- 阶段对比显微镜用于细胞迁移研究.
主要成果:
- 93种多类和单类化合物的特征,包括黄类糖化物,林类和基酸衍生物.
- 乙醇提取物显示出高抗氧化能力.
- 观察到针对 Bacillus subtilis 和 Streptococcus pyogenes 的显著抗菌活性.
结论:
- 拉瑟鲁斯结核的叶子含有丰富的生物活性化合物.
- 已证明的抗氧化和抗微生物活性支持L. tuberosus作为新型营养品来源的传统使用和潜在发展.
关键词:
这种植物是Lathyrus tuberosusus.在UHPLC-MS/MS中使用.抗微生物活性的抗微生物活性.抗氧化能力的抗氧化能力.细胞迁移 细胞迁移细胞毒性 细胞毒性纤维细胞的细胞.角质细胞 (keratinocytes) 是一种细胞.更多相关视频
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