在20-35岁的健康年轻成年人中探索炎症生物标志物和脂肪测量之间的联系
Irina Bianca Kosovski1,2, Vladimir Bacârea3, Dana Ghiga3
1Department of Pathophysiology, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, 540139 Târgu Mureș, Romania.
Nutrients
|January 23, 2024
概括
亚临床炎症与健康年轻人的多余体脂肪有关. 像hsCRP和WBC这样的炎症标志物与肥胖程度相关,这表明即使在年轻人群体中也存在健康风险.
科学领域:
- 免疫学和代谢健康
- 人体生理学和人体组成
背景情况:
- 肥胖和衰老与慢性炎症有关,这是各种疾病的常见因素.
- 亚临床炎症可能会在明显疾病之前发生,特别是在患有过度脂肪的年轻人中.
研究的目的:
- 在健康的年轻成年人 (20-35岁) 中调查关键炎症生物标志物和脂肪测量指标之间的关系.
- 为了比较正常体重和超重/肥胖个体之间的炎症概况和脂肪.
主要方法:
- 评估的炎症标志物:高灵敏度C反应蛋白 (hsCRP),IL-1β,IL-6,TNF-α,IFN-γ,以及白细胞计数 (WBC).
- 测量脂肪计:手臂,腰,部周长 (AC,WC,HC),总体脂肪量 (TBFM),内脏脂肪水平 (VFL),体重指数 (BMI),腰/部比 (WHR) 和腰/身高比 (WHtR).
- 根据BMI (正常体重与超重/肥胖) 和hsCRP水平分组参与者.
主要成果:
- 与正常体重的成年人相比,超重/肥胖的成年人表现出大多数炎症生物标志物的度明显更高.
- 在hsCRP,TNF-α,WBC和所有脂肪测量措施之间观察到正相关性.
- IL-6,IFN-γ和IL-1β与特定的肥胖指标有显著的相关性,突出了各种炎症关联.
结论:
- 在超重或肥胖的健康年轻人中存在亚临床炎症.
- 特定的炎症标志物与这个人口中的各种体脂和中央脂肪度相关.
- 这些研究结果强调了监测年轻人的炎症和身体组成的重要性,以确定潜在的健康风险.
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