涉及Burkholderia cepacia复合体的败血输血反应:一个审查
Margarita Salamanca-Pachon1, Nohora Isabel Guayacan-Fuquene1, Michel-Andres Garcia-Otalora2
1Blood Bank Sociedad de Cirugía de Bogotá, Hospital de San José, Bogotá 111411, Colombia.
Microorganisms
|January 23, 2024
概括
由于Burkholderia cepacia复合体 (Bcc) 污染而引起的输血传染病 (TTIs) 是罕见但严重的. 这次审查发现,在输血后发生了11例BCC血症,突出了改善预防策略的必要性.
科学领域:
- 微生物学 微生物学
- 传染性疾病 传染性疾病
- 血液学 血液学 血液学
背景情况:
- 输血传染病 (TTIs) 在医疗保健中构成重大风险.
- 伯克霍尔德里亚头皮复合体 (Bcc) 是一种机会性病原体,能够引起严重的感染.
研究的目的:
- 审查由Bcc污染的血液成分引起的TTIs的全球发病率.
- 为了分析经过输血后报告的BCC败血症病例.
- 识别风险因素并推出预防策略.
主要方法:
- 在多个专业数据库 (Medline/PubMed,科学网,Scopus,Scielo,ScienceDirect,ClinicalKey) 进行全面的文献搜索.
- 对11例报告的BCC输血相关性败血症病例的分析.
- 临床数据的比较检查,包括诊断,血液成分,症状发作,治疗和结果.
主要成果:
- 在输血后发现了11例BCC败血症 (8例发表,3例机构).
- 不管储存温度如何,各种血液成分都发生了BCC污染.
- 所有受影响的患者都有免疫系统受损;污染源多样化.
结论:
- 血液成分容易受到BCC污染,导致免疫受损患者的败血症.
- 不同的污染源需要多方面的预防策略.
- 实施加强的预防措施至关重要,以减少与BCC相关的输血风险.
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