多种小圆形DNA病毒在美国鼠便样本中被发现
Diego Olivo1, Anthony Khalifeh1, Joy M Custer1
1Biodesign Center for Fundamental and Applied Microbiomics, Center for Evolution and Medicine, School of Life Sciences, Arizona State University, Tempe, AZ 85042, USA.
Microorganisms
|January 23, 2024
概括
研究人员在美国 (Mareca americana) 便样本中发现了64个新的圆形DNA病毒基因组. 这项研究扩大了有关水禽病毒的知识,确定了许多新的Cressdnaviricota和Microviridae病毒.
科学领域:
- 病毒学 病毒学
- 鸟类学 鸟类学是一门学科.
- 环境科学 环境科学
背景情况:
- 有限的研究存在影响美国 (Mareca americana) 的病毒,之前的研究集中在orthomyxoviruses,冠状病毒和circoviruses.
- 关于与这种广泛分布的北美水鸟物种相关的病毒多样性,知识缺口仍然存在.
研究的目的:
- 为了在美国牛便样本中识别小圆形DNA病毒.
- 描述美国的环境和微生物群中的病毒多样性和潜在宿主.
主要方法:
- 一项试点研究利用了病毒元基因组工作流,专门针对圆形DNA病毒.
- 分析了亚利桑那州佩收集的一只美国的便样本.
- 病毒基因组的鉴定和分类基于序列同质,特别是复制相关的蛋白质.
主要成果:
- 确定了64种不同的圆形DNA病毒基因组.
- 45个基因组属于Cressdnaviricota类,其中包括3个来自Genomoviridae家族和42个未被分配到已知的病毒群.
- 19个基因组被确定为属于Microviridae家族,可能与肠道细菌有关.
结论:
- 这项研究显著扩大了与美国白色人种相关的已知病毒谱.
- 鉴定到的病毒,特别是新型的Cressdnaviricota,可能会感染鱼的饮食或环境中的各种生物.
- 微型病毒病毒很可能与美国的肠道微生物群有关,为宿主微生物相互作用提供了洞察力.
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