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Updated: Jul 5, 2025

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
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通过MPS1和CENPE抑制最大限度地提高抗癌反应,同时诱导亡

Bárbara Pinto1,2, João P N Silva1, Patrícia M A Silva1,3

  • 1UNIPRO-Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences (IUCS), Cooperativa de Ensino Superior Politécnico e Universitário (CESPU), Rua Central de Gandra, 1317, 4585-116 Gandra, Portugal.

Pharmaceutics
|January 23, 2024
PubMed
概括

将BH3-模拟剂与抗线虫药物 (如线虫阻断剂或驱动剂) 结合起来,可显著增强通过亡的癌细胞死亡. 这种组合疗法对非瘤细胞的毒性降低,改善了治疗潜力.

关键词:
这是一种BCL-2家族抑制剂.这是一种CENPE抑制剂.这是一种MPS1抑制剂.抗菌素的抗菌素是一种抗菌素.它具有抗瘤活性.癌症治疗 治疗 治疗 癌症组合疗法治疗组合治疗.

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