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H2-受体对抗剂对达科米替尼布暴露的影响

Jian Liu1, Swan Lin2, Anthony Huynh3

  • 1Clinical Pharmacology, Pfizer Investment Co., Ltd., Beijing 100010, China.

Pharmaceutics
|January 23, 2024
PubMed
概括

组胺-2受体对抗剂 (H2RAs) 在晚期非小细胞肺癌 (NSCLC) 患者中不会显著改变达科米替尼布的暴露. 这一发现支持H2RAs与达科米替尼布的同时使用,这对于管理NSCLC至关重要.

关键词:
这是一种EGFR抑制剂.达科米丁尼布的使用情况总体存活率 总体存活率药物动力学 药物动力学没有进展的生存率.质子抑制剂的使用

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