穿皮分支肺动脉干预对双心室性心脏病的运动能力,肺 perfusion 和右心室功能的影响:一个系统的审查
Renée S Joosen1, Jules P B Frissen1, Agnes van den Hoogen2,3
1Department of Pediatric Cardiology, University Medical Center Utrecht, Wilhelmina Children's Hospital, Utrecht, The Netherlands.
Cardiology in the young
|January 23, 2024
概括
穿皮肺动脉干预可以改善先天性心脏病 (CHD) 患者的运动能力和肺 perfusion. 然而,需要更多的研究来了解对右心室功能和各种心脏病患者群体的长期影响.
科学领域:
- 心脏病学 心脏病学
- 儿童心脏病学 儿童心脏病学
- 干预心脏病学 干预心脏病学
背景情况:
- 分支肺动脉狭窄是手术修复后的常见并发症,患有双心室先天性心脏病 (CHD) 的患者.
- 经常需要重新干预,但穿皮干预的长期结果仍然不清楚.
- 关于运动能力,右室功能和肺 perfusion 的现有数据是有限的.
研究的目的:
- 审查穿皮分支肺动脉干预对关键功能参数的长期影响.
- 综合目前关于运动能力,右心室功能和干预后肺 perfusion 的证据.
- 确定有关各种冠状动脉疾病患者群体结果的知识差距.
主要方法:
- 在PubMed,Embase和Cochrane数据库中进行系统的文献搜索.
- 包括专注于右心室功能,运动能力和穿皮支肺动脉干预后肺 perfusion 的研究.
- 研究选择,数据提取和质量评估由两位研究人员独立进行.
主要成果:
- 包括7项符合条件的研究 (330名患者),偏差风险低至中等.
- 有证据表明,干预后的运动能力和肺 perfusion 的改善.
- 没有足够的数据可以得出关于右心室功能,重塑或干预类型或特定心血管疾病群体之间的差异的结论.
结论:
- 关于肺动脉干预在双心室性心血管疾病的长期影响的数据很少.
- 短期随访表明增加运动能力和改善肺 perfusion 的潜力.
- 进一步的研究至关重要,以评估这些干预措施在各种心脏病患者群体中的影响.
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