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对控制功能性胃肠道疾病中的内脏过敏的草药制剂的系统审查
Naser-Aldin Lashgari1,2, Nazanin Momeni Roudsari1,2, Saeideh Momtaz3,4
1Department of Toxicology & Pharmacology, Faculty of Pharmacy, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Current pharmaceutical biotechnology
|January 23, 2024
概括
某些草药通过减少炎症和氧化应激,有效地管理易怒肠综合征 (IBS) 中的内脏过敏症 (VH). 这些天然疗法为胃肠道疾病的疼痛管理提供了有希望的替代方案.
科学领域:
- 胃肠病学 胃肠病学
- 药理学 药理学是指药理学的学科.
- 自然产品 自然产品
背景情况:
- 视觉过敏 (VH) 是胃肠道 (GI) 疾病的关键因素,如刺激性肠综合征 (IBS),其特征是疼痛反应加剧.
- 冠状炎的机制包括炎症,氧化应激和感觉运动变化,尽管尚未完全阐明.
研究的目的:
- 审查VH在胃肠道疾病中的病理生理学.
- 探索草药在风湿管理中的有效性,强调其抗炎和抗氧化特性.
- 评估草药治疗作为合成药物的替代品,具有潜在的不良影响.
主要方法:
- 2004年至2020年6月的英语语言研究的系统审查.
- 在PubMed,谷歌学者,Scopus和Cochrane图书馆进行的搜索.
- 包括临床和动物研究.
主要成果:
- 包括Radix,Melissia,Glycyrrhizae,Mentha和甘露在内的草药在治疗VH方面表现出显著的有效性.
- 这些草药对IBS和消化不良特别有效.
- 作用机制包括调节短暂受体潜在类型-1 (TRPV1) mRNA表达和抑制5-基胺3 (5-HT3) 受体.
结论:
- 草药配方在管理VH方面表现出积极的影响.
- 建议对新型草药和混合草药/化学制剂进行进一步的研究.
- 草药在肠道疾病的疼痛管理中是一个可行的选择.
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