使用心血管指数 (CAVI) 评估了COVID-19和动脉硬的关联
Valery Podzolkov1, Anna Bragina1, Aida Tarzimanova1
1Department of Faculty Therapy No. 2, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Current hypertension reviews
|January 23, 2024
概括
COVID-19患者的心血管指数 (CAVI) 值较高,表明动脉硬性增加. 这项研究发现,高CAVI和COVID-19之间存在显著的关联,即使在调整心血管风险因素后也是如此.
科学领域:
- 心血管健康 心血管健康
- 传染性疾病 传染性疾病
- 血管生物学 血管生物学
背景情况:
- COVID-19与急性炎症和内皮功能障碍有关,可能会影响动脉硬.
- 之前的研究没有调查COVID-19患者的心血管指数 (CAVI),考虑到心血管风险因素.
研究的目的:
- 在住院患者中评估心血管指数 (CAVI) 与COVID-19之间的关联.
- 在这种关联中调整已知的心血管风险因素.
主要方法:
- 一项横截面研究比较了174名住院COVID-19患者和94名对照人群.
- 心血管指数 (CAVI) 值使用VaSera VS - 1500N进行测量.
- 多变量逻辑回归分析了COVID-19和增加的CAVI (≥9.0) 之间的独立关联,并根据年龄,高血压,葡萄糖,GFR和糖尿病进行调整.
主要成果:
- 与对照组相比,COVID-19患者表现出明显更高的右和左CAVI值.
- 多变量分析显示,高CAVI和COVID-19之间存在显著的关联 (OR 2.41 [CI 1.09;5.30]).
- 在调整了关键心血管风险因素后,这种关联仍然显著.
结论:
- 住院COVID-19患者的心血管指数 (CAVI) 值显著增加.
- 在高CAVI和COVID-19之间存在独立的关联,无论常见的心血管风险因素如何.
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