儿童局部过敏性鼻炎:在专业门诊诊所进行鉴定和鉴定
F Y Matsumoto1, T R Tranquillini Gonçalves1, D Solé1
1Division of Allergy, Clinical Immunology and Rheumatology, Department of Pediatrics, Universidade Federal de São Paulo, São Paulo, Brazil.
儿童和青少年局部过敏性鼻炎 (LAR) 经常被误诊. 这项研究发现,40%的非过敏性鼻炎患者实际上患有LAR,这突显了鼻子过敏原挑战 (NAC) 对于准确诊断的重要性.
科学领域:
- 儿科过敏和免疫学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 临床诊断 临床诊断 临床诊断
背景情况:
- 局部过敏性鼻炎 (LAR) 的特点是过敏性鼻炎的症状没有系统性敏感化.
- 目前关于儿科LAR的数据有限,特别是来自拉丁美洲的数据.
- 准确区分LAR和非过敏性鼻炎 (NAR) 是临床上具有挑战性的.
研究的目的:
- 调查拉丁美洲儿科患者中LAR的患病率和特征.
- 为了确定患有鼻炎的儿童和青少年以及可能患有LAR的负面系统敏感化测试.
- 为了评估鼻过敏原挑战 (NAC) 在诊断LAR在这个人群中的实用性.
主要方法:
- 鼻腔过敏素挑战 (NAC) 针对患有鼻炎和阴性皮肤刺伤测试 (SPT) 的儿科患者 (6-18岁) 进行.
- 使用的过敏原包括皮肤虫 pteronyssinus 和Blomia tropicalis.
- 通过主观参数和声学鼻计,评估了NAC的结果.
主要成果:
- 在758名患者中,517人患有鼻炎,95人 (18.4%) 呈阴性SPT.
- 25名患者接受了NAC;40% (10/25) 的患者呈阳性NAC.
- 这10名患者被从NAR重新分类到LAR,这表明该亚组的临床误诊.
结论:
- 这项研究是拉丁美洲首次调查儿科LAR的研究,揭示了显著的患病率.
- 在最初被诊断为NAR的儿科患者中,很大一部分 (40%) 在NAC之后被重新归类为LAR.
- NAC是一种安全,可行的,对于准确诊断儿童和青少年LAR至关重要的工具.
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