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Updated: Jul 5, 2025

An In Ovo Model for Testing Insulin-mimetic Compounds
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一种口服的化合物抑制了葡萄糖的高分泌,并使1型糖尿病的高血糖正常化

Farzad Asadi1, Subhadra C Gunawardana1, Roland E Dolle2

  • 1Department of Cell Biology and Physiology and.

JCI insight
|January 23, 2024
PubMed
概括

使用WCDD301针对阿尔法细胞上的EphA4受体显示出1型糖尿病 (T1D) 的前景. 这种小分子激动剂在临床前模型中降低了葡萄糖分泌并使血糖正常化,为T1D提供了潜在的新疗法.

关键词:
糖尿病 糖尿病 糖尿病内分泌学 在内分泌学.

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