环境温度与高风险人群中风风险之间的关联:系统性审查
Nathan Danh1, Chau Ho2, Emily Ford1
1Curtin Medical School, Faculty of Health Sciences, Curtin University, Perth, WA, Australia.
Frontiers in neurology
|January 23, 2024
概括
极端温度会增加高风险个体中风的风险. 寒冷和热量都与较高的中风率有关,特别是在心脏病患者中,这凸显了需要采取保护措施的必要性.
科学领域:
- 环境健康 环境健康
- 心血管流行病学心血管流行病学
- 神经学 神经学
背景情况:
- 环境温度和中风风险之间的关联已经确立,但对高心血管风险人群的证据仍然有限.
- 本系统性审查综合了当前关于环境温度对这一特定人口群体中整体中风风险的影响的研究.
研究的目的:
- 系统地审查和总结当前关于环境温度与中风风险之间的关联的证据.
- 在高风险人群中,研究温度对不同类型的中风亚型的影响,包括缺血性中风 (IS),内脑出血 (ICH) 和下关节出血 (SH).
主要方法:
- 从创立到2023年7月,在多个数据库 (MEDLINE,Embase,PsycINFO,CINAHL,Web of Science,GEOBASE) 进行了全面的文献搜索.
- 基于人群的研究,包括年龄在18岁及以上,至少80%的高心血管疾病风险概况的个体,是符合条件的.
- 脑卒中发病率和死亡率是主要结果;IS,ICH和SH结果是次要的.
主要成果:
- 较低的环境温度与出血和缺血性中风的发病率和死亡率增加有关,特别是在老年人中.
- 较高的环境温度与内出血风险增加有显著的关联,但缺血性中风风险降低.
- 无论环境温度高低,在患有诸如充血性心力衰竭和脂质失调等并发症的患者中都会持续增加中风风险.
结论:
- 环境温度显著影响高心血管风险的个体中风风险.
- 有证据表明,需要制定临床指导方针,以管理脆弱人群在极端温度事件期间的中风风险.
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