多重耐药细菌与重症监护室患者的结果之间的关联:一项非干预性研究
Alessandro Pacheco Silveira Martins1,2, Camila Pacheco Silveira Martins da Mata1, Uener Ribeiro Dos Santos3
1Hospital Risoleta Tolentino Neves, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Frontiers in public health
|January 23, 2024
概括
在重症监护室 (ICU) 监测多药耐药 (MDR) 微生物对于预防医疗相关感染 (HAI) 至关重要. 这项研究在9.5%的ICU患者中发现了MDR细菌,与特定疾病和抗微生物药物的使用相关的死亡率更高.
科学领域:
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
- 微生物学 微生物学
背景情况:
- 重症监护病房 (ICU) 是医疗相关感染 (HAI) 的高风险环境.
- 监测多药耐药 (MDR) 微生物对于控制ICU感染传播至关重要.
研究的目的:
- 调查MDR微生物在ICU中的流行情况.
- 为了确定与ICU患者感染或感染MDR细菌的死亡率相关的风险因素.
主要方法:
- 从2018年到2020年,对ICU患者的病历进行了回顾性分析.
- 包括所有被MDR微生物殖民/感染的患者,接受主动监测培养 (ASC).
主要成果:
- 9.5%的ICU患者的MDR细菌检测结果呈阳性,耐卡巴尼姆的肠道细菌是最常见的.
- 在老年患者,那些具有侵入性设备的患者和那些患有并发症的患者中,住院死亡率显著更高.
- 梅罗和万科米辛的使用与HAI诊断/演变有关,而宏类药物显示出对死亡率的保护作用.
结论:
- 患有MDR细菌,侵袭性设备和潜在疾病的ICU患者面临的死亡率增加.
- 对于患有或有HAI风险的患者,建议仔细监测梅罗和万科米辛的处方.
相关概念视频
Healthcare Associated Infections II: Preventive Measures
2.6K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.6K
Combined Effects of Drugs: Synergism
3.9K
Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
Such synergistic combinations...
Such synergistic combinations...
3.9K
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
4.2K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
4.2K
Antibiotic Selection
53.7K
Overview
53.7K
Pulmonary Tuberculosis V
180
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
180
Pneumonia IV: Management
331
The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
331


