相关实验视频

Updated: Jul 5, 2025

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

Published on: December 18, 2016

在住院患者感染SARS-CoV-2后,COVID引起的大脑功能障碍的决定因素

Shahwar Yasir¹, Yu Jin¹, Fuleah A Razzaq¹

¹Joint China-Cuba Laboratory for Neurotechnology and Bioengineering (JCCLNB), The Clinical Hospital of Chengdu Brain Science Institute, School of Life Sciences and Technology, University of Electronic Science and Technology of China, Chengdu, China.

Frontiers in neuroscience

|January 23, 2024

概括

COVID-19幸存者面临的神经和神经精神疾病风险增加,特别是那些有先前存在的疾病的人. 早期诊断和全面的随访对于长期管理COVID后症状至关重要.

科学领域:

神经科学是一个神经科学.
传染性疾病传染性疾病
公共卫生公共卫生

背景情况:

COVID-19 流行病对全球健康和社会造成了毁灭性的后果.
SARS-CoV-2 感染与神经和神经精神疾病的发病率较高有关.
了解COVID-19后的长期影响,特别是神经精神症状,至关重要.

研究的目的:

调查健康状况前期,COVID-19严重程度和COVID-19后期神经精神症状 (COVID后NPS) 之间的关系.
为了确定与发展严重的COVID-19和长期神经精神疾病后果相关的风险因素.
为了检查在COVID-19幸存者中普遍存在的特定神经精神病症状.

主要方法:

一项涉及178名古巴受试者的横截面研究,包括住院COVID-19患者和健康对照.
使用物件响应理论 (IRT) 为健康前条件 (PHC) 构建潜在变量.
用因子分析 (FA) 和结构方程建模 (SEM) 来分析变量之间的关系,控制混因素.

主要成果:

预先健康状况 (PHC) 和COVID前的认知障碍显著预测了COVID-19的严重程度 (p < 0.001).
COVID-19严重程度是后COVID-NPS增强的强有力的预测指标 (p < 0.001),即使调整年龄,性别和先前存在的神经心理症状.
心血管疾病,糖尿病和高血压是PHC的关键决定因素. 性和COVID前的神经精神疾病 (神经病变,精神病,认知问题,成) 与COVID后的NPS有显著的关联.

结论:

患有先前并发症或神经精神疾病的COVID-19患者面临更高的严重疾病和长期后COVID-NPS的风险.
这项研究突出了从健康状况到COVID-19严重程度的潜在因果途径,随后是神经精神病的后果.
对所有COVID-19患者,包括严重病例和无症状幸存者,全面的神经精神病学随访至关重要.

关键词:

在 COVID-19 疫情中,这就是SARS-CoV-2病毒.长时间的COVID.神经心理学神经心理学后COVID神经精神疾病症状/疾病.

更多相关视频

Author Spotlight: Bridging Gaps in Anatomy and Establishing a Foundation for Algorithmic Studies

Author Spotlight: Bridging Gaps in Anatomy and Establishing a Foundation for Algorithmic Studies

Published on: December 15, 2023

Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury

Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury

Published on: November 19, 2012

相关概念视频

Factors Affecting the Risk of Infection

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...

Biological Causes of Schizophrenia

Biological Causes of Schizophrenia

Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...