试管婴儿治疗涉及体重增加的神话是否有任何真相?
Bozhena Saar-Ryss1,2, Michael Shilo3, Michael Friger3
1IVF Unit, Barzilai University Medical Center, Ashkelon, Israel.
Frontiers in reproductive health
|January 23, 2024
概括
试管婴儿 (IVF) 激素治疗不会导致显著的体重增加. 这项研究发现体重变化很小,揭穿了患者对生育治疗的担忧.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 临床妇科 临床妇科
背景情况:
- 在辅助生殖技术 (ART) 中使用的激素疗法通常与患者对体重增加的担忧有关.
- 了解这些疗法对体重的实际影响对于患者的咨询和遵守至关重要.
研究的目的:
- 为了前性地评估在接受体外受精和胚胎移植 (IVF-ET) 的妇女的体重变化,使用对抗剂协议.
- 评估最多三次治疗周期的体重波动,并根据体重指数 (BMI) 分析变化.
主要方法:
- 一项前性队列研究包括2018年至2019年期间接受试管婴儿治疗的IVF患者.
- 在治疗前,在激素刺激开始时和周期结束时 (怀孕测试日) 进行体重测量.
- 在正常体重,超重和肥胖的BMI组中分析了519个周期的数据.
主要成果:
- 第一个,第二个和第三个IVF-ET周期后的平均总体重变化是最小的 (分别为初始体重的0.36%,0.56%,0.23%).
- 这些变化在临床上是无意义的,远低于显著体重增加的5%-7%门.
- 在所有BMI组中,体重变化仍然低于1%,这表明没有临床上显著的影响.
结论:
- 研究结果驳斥了试管婴儿激素治疗导致临床上显著的体重增加的观点.
- 这些结果可以缓解患者的焦虑,并提高辅助生殖技术治疗的接受度.
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