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骨肌肉重编程可以在外围神经受伤后增强神经回收

Pihu Mehrotra1, James Jablonski2, John Toftegard3

  • 1Department of Chemical and Biological Engineering, University at Buffalo, Buffalo, NY 14260, USA.

Research square
|January 23, 2024
PubMed
概括

用NANOG重新编程骨肌肉可以在外周神经受伤后保持重新内化. 这种方法增强了肌肉发育和运动功能的恢复,为治疗神经损伤提供了新的策略.

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Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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