后运动神经元的脊柱上控制通过脊髓刺激启用脊髓刺激
Marco Capogrosso1, Josep-Maria Balaguer2, Genis Prat-Ortega1
1University of Pittsburgh.
Research square
|January 23, 2024
概括
脊髓刺激 (SCS) 直接激活运动神经元,而不是通过促进现有的信号. 剩余的大脑输入完善了这种激活,使后的有限的意志控制成为可能.
科学领域:
- 神经科学是一个神经科学.
- 生物医学工程 生物医学工程
- 康复医学 康复医学 康复医学
背景情况:
- 脊髓刺激 (SCS) 是在脊髓损伤 (SCI) 和中风后恢复运动功能的有希望的治疗方法.
- 以前的假设表明,SCS增强了对运动神经元的剩余脊柱上输入.
结论:
- SCS直接激活脊柱运动神经元,解释其在运动恢复中的有效性.
- 随意控制SCS介导活动是可能的,但受到脊上通道完整性的约束.
- 这项研究澄清了SCS机制,并预测了严重SCI或中风病例的局限性.
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