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Updated: Jul 5, 2025

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活性HER4和HER2/HER4复合体的结构动力学受到不同的生长因子和糖化酶的微调

Raphael Trenker1, Devan Diwanji1,2, Tanner Bingham1

  • 1Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA 94158, USA.

bioRxiv : the preprint server for biology
|January 23, 2024
PubMed
概括

对人体表皮生长因子受体4 (HER4) 激活的结构洞察力揭示了同位体与HER2异位体的不同动态. 甘氨酸的修改稳定了HER4同位体,影响了受体功能.

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