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Updated: Jul 5, 2025

A Method for Measuring RNA N6-methyladenosine Modifications in Cells and Tissues
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使用半监督学习框架从纳米孔测序检测m6ARNA修饰

Haotian Teng1, Marcus Stoiber2, Ziv Bar-Joseph1

  • 1Computational Biology Department, Carnegie Mellon Univeristy, Pittsburgh PA 15213, USA.

bioRxiv : the preprint server for biology
|January 23, 2024
PubMed
概括

一种新型的基调器Xron,可以从纳米孔测序信号直接准确地检测RNA N6-甲基氨酸 (m6A) 甲基化. 这种方法克服了数据稀缺性,使得有效的de novo甲基组组装成为可能.

关键词:
深度学习是一种深度学习.纳米孔测序的测序隐藏的马尔科夫模型m6A 是一种RNA修饰.

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RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
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