血压的变化与美国成年人的骨质损失有关:NHANES 2005-2018年跨部分研究
Shixuan Liu1, Shaobo Wu1, Xueyuan Bao2
1Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, 710054, China.
Calcified tissue international
|January 23, 2024
概括
骨质疏松症与老年人高血压有显著的联系,在一项大型美国人口研究中发现了显著的关联. 需要进一步的研究来了解影响这种关系的复杂因素.
科学领域:
- 老年医学 老年医学
- 心血管健康 心血管健康
- 骨的新陈代谢 骨的新陈代谢
背景情况:
- 高血压和骨质疏松症是老年人群中普遍存在的疾病.
- 共同的风险因素表明这两种疾病之间存在潜在的联系.
研究的目的:
- 调查高血压和骨质疏松症之间的关联.
- 探索影响变量和潜在因果关系.
主要方法:
- 分析了2005-2018年国家健康和营养检查调查 (NHANES) 的12787名参与者.
- 逻辑回归用于关联,线性/非线性回归用于血压和骨密度/含量.
- 机器学习用于因素重要性和孟德尔随机化用于因果关系.
主要成果:
- 骨质疏松症与高血压有显著的积极关联 (OR 2.072).
- 在对共变量 (OR 1.223) 进行调整后,这种关联仍然显著.
- 该研究发现,骨质疏松症和高血压在美国人口中存在正相关性.
结论:
- 骨质疏松症和高血压之间存在显著的关联.
- 各种因素影响了这种关系,需要进一步研究监管机制和混因素.
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