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Updated: Jul 5, 2025

Crystal Structure of the N-terminal Domain of Ryanodine Receptor from Plutella xylostella
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Published on: November 30, 2018

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使用FFTK和FFParam使用Ryanodine受体抑制药物dantrolene的CHARMM力场参数的优化

Saliha Nur Uludag1, Cemil Can Saylan1,2, Adem Tekin1,3

  • 1Computational Science and Engineering Department, Informatics Institute, Istanbul Technical University, Ayazaga Campus, Maslak, 34469, Istanbul, Türkiye.

Journal of molecular modeling
|January 23, 2024
PubMed
概括

为了帮助计算机辅助的药物设计和恶性热升高 (MH) 治疗的分子动力学研究,开发了dantrolene的精确力场参数. 这项研究支持新型RyR抑制剂的开发和理解dantrolene.

关键词:
丹特罗烯是一种丹特罗烯.在FFPFaram.FFTK FFTK 在线交易平台实力场是一个力场.瑞亚诺丁受体的受体

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