基于ICP-MS的三重四极系统的开发和优化,用于预先缩的气态基本的量化
Tsuyoshi Shintani1,2, Akinori Takeuchi3
1National Institute for Environmental Studies, 16-2 Onogawa, Tsukuba, Ibaraki, 305-8506, Japan. shintani-tsuyoshi@hro.or.jp.
概括
一种新方法使用热溶解与ICP-MS相结合,精确测量同位素. 这一进步有助于追踪污染及其对健康的影响.
科学领域:
- 环境化学环境化学
- 分析化学 分析化学
- 毒理学 毒理学 毒理学
背景情况:
- 了解 (Hg) 转化对于预测环境水平和健康影响至关重要.
- 稳定的同位素是Hg生产速度的有价值的标记物.
- 现有的Hg量化方法在同位素分化和检测极限方面存在局限性.
研究的目的:
- 开发和评估一台定制的热溶解装置,与三重四极ICP-MS (ICP-QQQ) 直接合,用于超微量Hg量化.
- 为了实现环境研究的精确Hg同位素测量.
- 改进现有的气态元素Hg (Hg0) 的分析技术.
主要方法:
- 开发了一种定制的热溶解装置,并直接与ICP-QQQQ相合.
- 该系统使用Hg标准气体和从水性标准生成的Hg 0进行了验证.
- 超微量Hg0预先集中在Au陷上进行分析.
主要成果:
- 开发的系统实现了超微量Hg0检测和精确的Hg同位素测量 (分析误差≤3.5%).
- 对于Hg度在0-300 pg之间观察到出色的线性 (r 2 > 0.999),方法检测极限为0.01-0.03 pg Hg.
- 最新的ICP-QQQ (Agilent 8900) 显示出更高的灵敏度 (大约. 与Agilent 8800相比,5倍高) 和同时进行多同位素分析.
结论:
- 定制的热溶解-ICP-QQQ系统为Hg同位素分析提供了灵敏而精确的方法.
- 这种技术克服了传统方法的局限性,使Hg污染能够更好地跟踪.
- 改进的分析能力有助于更准确地评估Hg转化速率和人为影响.
相关概念视频
01:19Inductively Coupled Plasma–Mass Spectrometry (ICP–MS): Overview
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In inductively coupled plasma–mass spectrometry (ICP–MS), an inductively coupled plasma (ICP) torch is used as an atomizer and ionizer. Solid samples are dissolved and volatilized before being introduced into the high-temperature argon plasma, while solution samples are nebulized and passed through the high-temperature argon plasma. Plasma dissociates the analytes and ionizes their component atoms to form a mixture of positive ions and molecular species. The positive ions are then...
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01:20Inductively Coupled Plasma-Mass Spectrometry (ICP-MS): Interferences
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Inductively coupled plasma–mass spectrometry (ICP–MS) is a highly selective and sensitive technique for accurate elemental analysis. Though the analysis of ICP–MS mass spectra is comparatively straightforward, it is affected by spectroscopic and non-spectroscopic interferences. Spectroscopic interferences arise when the plasma contains ionic species with an m/z value the same as the analyte ion. Spectroscopic interference can be categorized as isobaric, polyatomic ions, and...
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01:19Inductively Coupled Plasma Atomic Emission Spectroscopy: Principle
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Inductively coupled plasma (ICP) is the most widely used plasma source in atomic emission spectroscopy (AES), also known as Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES). The ICP source, or torch, consists of three concentric quartz tubes with argon gas flowing through them. A spark from a Tesla coil initiates the ionization of argon, generating a high-temperature plasma.
The ions and electrons produced interact with the fluctuating magnetic field created by a water-cooled...
The ions and electrons produced interact with the fluctuating magnetic field created by a water-cooled...
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01:19Mass Analyzers: Common Types
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The quadrupole mass analyzer consists of four cylindrical metal rods arranged in a diamond carrying a DC voltage and a radio-frequency AC voltage. The motion of ions through the quadrupole depends on the field strength, causing only ions of a certain m/z to resonate successfully and strike the detector at a given field strength. Though the transmission rate for these analyzers is high, the exact elemental composition of the sample is not determined because of low resolution; however, they are...
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01:14Gas Chromatography–Mass Spectrometry (GC–MS)
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Gas chromatography–mass spectrometry (GC–MS) is the combination of analytical techniques of gas chromatography and mass spectrometry in a single instrument for analyzing a mixture of compounds. The gas chromatograph separates the compounds in the mixture, and the mass spectrometer analyzes each compound separately to determine the molecular masses and molecular structures.
A gas chromatograph consists of a long, narrow capillary column with a polysiloxane coating on the inner wall....
A gas chromatograph consists of a long, narrow capillary column with a polysiloxane coating on the inner wall....
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01:21Mass Spectrometry: Complex Analysis
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Mass spectrometry is an important technique for the identification of pure compounds. However, it has some limitations for the analysis of complex mixtures, often due to excessive fragmentation making the spectrum too complicated to decipher. Mass spectrometry can be combined with suitable separation methods in sequence, forming hyphenated methods, which are useful in the analysis of complex mixtures.
GC–MS is a powerful hyphenated method commonly used in forensics and environmental...
GC–MS is a powerful hyphenated method commonly used in forensics and environmental...
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