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[自闭症的生物化学标志物]
I G Samoilova1, M V Matveeva1, D E Galyukova1
1Siberian State Medical University, Tomsk, Russia.
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
|January 23, 2024
概括
自闭症谱系障碍 (ASD) 诊断由于行为观察主观性而具有挑战性. 本综述探讨了新兴的生物生物标志物,以改善早期和准确的ASD检测和治疗.
科学领域:
- 神经科学是一个神经科学.
- 发展生物学 发展生物学
- 遗传学 遗传学 是一个
背景情况:
- 自闭症谱系障碍 (ASD) 是一种复杂的神经发育障碍,患病率越来越高.
- 目前的自闭症诊断依赖于行为观察,这在准确性和客观性方面提出了重大挑战.
- 对可靠的生物标志物的需求对于早期检测和有效干预至关重要.
研究的目的:
- 审查关于自闭症谱系障碍 (ASD) 生物标志物的研究现状.
- 突出了确定ASD客观生物指标的进展.
- 讨论生物标志物在改善ASD诊断和管理方面的潜力.
主要方法:
- 关于ASD生物标志物的综合文献综述研究.
- 分析着重于与ASD相关的生物异常的研究.
- 对目前正在开发中的各种生物标志物候选物的研究结果的综合.
主要成果:
- 过去二十年来,大量的研究工作都集中在识别ASD中的特定生物异常.
- 目前正在研究各种潜在的生物标志物,包括遗传,分子和神经成像标志物.
- 在了解ASD的生物学基础方面正在取得进展.
结论:
- 生物标志物对客观的自闭症诊断有很大的前景,超越了主观的行为评估.
- 进一步的研究对于验证和将这些生物标志物转化为临床实践至关重要.
- 可靠生物标志物的开发可以彻底改变ASD的早期检测,干预和个性化治疗策略.
相关概念视频
01:19Autism Spectrum Disorder
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Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
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01:30Attention-Deficit/Hyperactivity Disorder
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Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
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