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Updated: Jul 5, 2025

Simultaneous Measurement of HDAC1 and HDAC6 Activity in HeLa Cells Using UHPLC-MS
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Published on: August 10, 2017

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含有RAS/RAF蛋白干扰单元的多目标HDAC抑制剂

Yuanjiang Wang1,2, Jianluo Zhang1, Kun Li1

  • 1Pharmaceutical Research Center and School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, PR China.

Journal of medicinal chemistry
|January 23, 2024
PubMed
概括

新的抗癌药物,XSJ-7和XSJ-10,向激素脱乙酶 (HDAC) 和RAS通路. 在临床前模型中,XSJ-10表现出强大的抗瘤活性和有利的药理动力学.

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