伪菌 (Pseudomyxoma peritonei) 的起源和生存结果 - 一个回顾性研究
Sangeetha K Nayanar1, Anu Jose Markose2, Manuprasad Avaronnan3
1Clinical Lab Services and Translational Research, Malabar Cancer Centre, Thalaserry, Kannur, Kerala, India.
Journal of cancer research and therapeutics
|January 23, 2024
概括
瘤 (Pseudomyxoma peritonei,简称PMP) 最常见的是源于尾,即使主要瘤没有明显的. 对于疑似PMP病例,建议进行早期尾切除.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 病理学 病理学 病理学
背景情况:
- 膜瘤 (Pseudomyxoma peritonei,简称PMP) 是一种罕见的疾病,其特征是粘膜和腹膜病变.
- 它的起源和预后一直在争论,重点是尾的起源.
研究的目的:
- 为了调查PMP的组织学起源.
- 分析在区域癌症中心治疗的PMP患者的生存结果.
主要方法:
- 在五年内对15个PMP病例进行了回顾性分析.
- 对临床病理学数据,组织学幻灯片和免疫组织化学标记物的审查.
- 使用了卡普兰-梅尔生存分析.
主要成果:
- 大多数PMP病例 (93.3%) 发现其起源于尾.
- 腹部膨胀 (53.3%) 和急性尾炎 (20%) 是常见的表现.
- 12个月和18个月的总生存率分别为50%和37%.
结论:
- 附录来源是PMP最常见的来源.
- 在怀疑PMP的情况下建议切除尾,无论粗略或放射性发现如何.
- 免疫组织化学对于识别隐藏的初级尾部位至关重要.
更多相关视频
09:19Culture and Imaging of Ex Vivo Organotypic Pseudomyxoma Peritonei Tumor Slices from Resected Human Tumor Specimens
Published on: December 9, 2022
1.8K
06:46Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
270
相关概念视频
History of Microbiology
Microbiology, a scientific field dedicated to the study of microorganisms, has undergone profound development since its inception in the 17th century. Its history is marked by key discoveries and technological advancements that have shaped our understanding of life at the microscopic level and transformed medicine, agriculture, and industry.Early Foundations of MicrobiologyThe early foundations of microbiology were built on groundbreaking observations and the development of pioneering...
Microbiota of the Stomach and Small Intestine
The human gastrointestinal (GI) tract is characterized by distinct physicochemical conditions that shape its microbial communities. Among these, the stomach presents a particularly challenging environment for microbial colonization due to its highly acidic pH, ranging from 1 to 3. This extreme acidity effectively limits microbial density. However, certain acid-tolerant microorganisms are capable of surviving in this niche. Notably, Helicobacter pylori can colonize the gastric mucosa,...
Atypical Pneumonia
Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Amebiasis
Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Gastritis II: Pathophysiology
The pathophysiology of gastritis begins with the colonization of the stomach lining by Helicobacter pylori (H. pylori). This bacterium spreads mainly via the oral-oral route through saliva or shared utensils, and can also be transmitted in overcrowded or unhygienic environments through contaminated water, despite its brief survival outside the body.ColonizationOnce ingested, H. pylori enters the stomach and begins colonization by navigating through the mucus layer lining the stomach wall. It...
