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Updated: Jul 5, 2025

Yeast Luminometric and Xenopus Oocyte Electrophysiological Examinations of the Molecular Mechanosensitivity of TRPV4
12:09

Yeast Luminometric and Xenopus Oocyte Electrophysiological Examinations of the Molecular Mechanosensitivity of TRPV4

Published on: December 31, 2013

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实验和计算生物物理学,以识别针对TRPV2的血管扩展药物,使用基于probenecid支架的激动剂

Èric Catalina-Hernández1,2, Mario López-Martín1,2, David Masnou-Sánchez1,2

  • 1Unit of Biophysics, Dept. of Biochemistry and Molecular Biology, Facultat de Medicina, Universitat Autònoma de Barcelona, 08193 Cerdanyola del Vallés, Catalonia, Spain.

Computational and structural biotechnology journal
|January 23, 2024
PubMed
概括

研究人员确定了新型TRPV2激动剂,包括4- ((piperidine-1-sulfonyl) -酸,它对治疗高血压具有性别特异性的效果. 这扩大了有限的TRPV2药物发现选项.

关键词:
生物物理学的生物物理.心血管疾病的心血管疾病计算生物学是一种计算生物学.停靠的对接方式药物发现 药物发现离子通道的离子通道膜蛋白是一种膜蛋白.药理学 药理学是指药理学的学科.结构生物学是结构生物学.在 TRP 频道.在 TRPV2 中.

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