在早产新生儿中,CPAP失败的预测因素与RAM管接口用于初级呼吸支持
Pradeep Kumar1, Anita Yadav2, Pratima Anand3
1Senior Resident (Pediatrics), Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi, India.
Medical journal, Armed Forces India
|January 23, 2024
概括
新生儿鼻持续正气道压力 (nCPAP) 的RAM接口显示出31.2%的失败率,早产婴儿的失败率更高. 然而,与其他CPAP接口相比,它造成的鼻损伤较少.
科学领域:
- 新生儿医学 新生儿医学
- 呼吸系统支持 呼吸系统支持
- 儿科重症监护中心儿童重症监护中心
背景情况:
- 在新生儿护理中,RAM管是提供鼻腔连续正气道压力 (nCPAP) 的常见接口.
- 支持其使用的临床证据有限.
- 本研究评估了RAM接口在临床环境中的有效性和安全性.
研究的目的:
- 使用RAM接口,在72小时内确定CPAP失效率.
- 评估与RAM接口使用相关的鼻子创伤的发生率和严重程度.
- 为了确定与新生儿CPAP失败相关的因素.
主要方法:
- 在第三级护理新生儿病房进行前性队列研究.
- 包括需要非侵入性呼吸辅助的早产新生儿 (妊娠28-32周,>1000g).
- 在治疗开始后72小时内监测CPAP失败率和鼻创伤.
主要成果:
- 整体CPAP失败率为31.2% (78/250名新生儿).
- 在怀孕28-30周之间的新生儿中,失败率明显高 (52.1%) 与31-32周 (18.2%) 相比.
- 鼻子创伤发生在14%的新生儿中,大多是轻微的.
结论:
- 使用RAM接口的临床结果与其他接口可比.
- RAM 接口显示鼻损伤的发生率较低.
- 需要进一步的随机试验来比较CPAP接口,特别是在发展中国家.
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