作为稳定慢性阻塞性肺病患者身体活动指标的相位角度
Takeshi Kobayashi1, Tomoyuki Murakami1, Hiroto Ono1
1Department of Rehabilitation, Tohoku Medical and Pharmaceutical University Wakabayashi Hospital, Yamatomachi, Wakabayashi-ku, Sendai, Japan.
Nutrition (Burbank, Los Angeles County, Calif.)
|January 23, 2024
概括
慢性阻塞性肺病 (COPD) 患者的相角 (PhA) 与体力活动 (PA) 有关. 更高的PhA与增加的高强度光PA和中度至强烈的PA相关,这表明PhA反映了活动水平.
科学领域:
- 生物医学科学 生物医学科学
- 生理学 生理学 生理学
- 肺部医学 肺部医学
背景情况:
- 阶段角 (PhA) 是细胞膜完整性和活力的标志物,通常表明肉症.
- 已知PhA与稳定的慢性阻塞性肺病 (COPD) 患者的身体功能相关.
- 在COPD中PhA和体力活动 (PA) 之间的关系以前没有被探索.
研究的目的:
- 在稳定的COPD患者中调查相角 (PhA) 和体力活动 (PA) 之间的关联.
主要方法:
- 一项涉及103名稳定的COPD患者的横截面观察研究.
- 用生物电阻分析测量相角 (PhA).
- 通过测量高强度光 PA (HLPA) 和中度至强度 PA (MVPA) 的持续时间来评估体力活动 (PA).
主要成果:
- 与PhA较低的患者相比,PhA较高的患者表现出HLPA和MVPA的持续时间明显更长.
- PhA与HLPA (r = 0.32) 和MVPA (r = 0.49) 显示出显著的正相关性.
- MVPA和HLPA仍然与PhA相关,无论各种临床和功能参数如何.
结论:
- 阶段角 (PhA) 似乎是COPD患者体力活动 (PA) 水平的有价值指标.
- 在这个人群中,PhA可以作为一个有用的生物标志物,反映肌肉功能和身体活动.
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