了解运动反应的变化,以指导个性化的身体活动处方
John Noone1, Justine M Mucinski1, James P DeLany1
1Translational Research Institute, AdventHealth, Orlando, FL 32804, USA.
Cell metabolism
|January 23, 2024
概括
个性化炼需要理解为什么个体对身体活动的反应不同. 本综述探讨了影响运动反应和健康结果的内在和外在因素.
科学领域:
- 运动生理学 运动生理学
- 分子生物学分子生物学
- 个性化医疗是个性化的医疗.
背景情况:
- 个体对运动的反应有很大差异,这阻碍了个性化处方.
- 了解这些变异对于优化健康结果至关重要.
- 分子和机械因素在运动反应中起着关键作用.
研究的目的:
- 审查影响运动反应变化的外部和内在因素.
- 检查运动的分子传感器及其对生理结果的影响.
- 识别开发个性化运动处方的挑战.
主要方法:
- 对影响运动反应的分子和机械因素的文献综述.
- 对外部因素 (如饮食,睡眠,药物) 的分析.
- 分析内在因素 (例如遗传学,性别,年龄,种族/民族).
主要成果:
- 诸如运动时间,饮食和睡眠等外部因素会影响运动反应.
- 包括遗传学,性别和年龄在内的内在因素是变异性的组成部分.
- 分子路径 (基因组,蛋白质组,代谢组) 介导运动效应.
结论:
- 开发个性化的运动处方需要全面了解反应变异性.
- 物理活动分子转换器联盟 (MoTrPAC) 解决了知识差距.
- 需要对不同人群和健康结果进行进一步的研究.
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