高近视的视神经病变:光眼或高近视或两者兼而有之?
Xiulan Zhang1, Jingwen Jiang1, Kangjie Kong1
1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, 510060, China.
Progress in retinal and eye research
|January 23, 2024
概括
高近视可导致视神经损伤类似于玻璃眼,造成诊断挑战. 本综述使用成像和视觉现场测试来区分这些情况,以指导管理.
科学领域:
- 眼科医生 眼科 眼科
- 视觉神经病变是一种视觉神经病变.
- 高近视研究 高近视研究
背景情况:
- 高近视是全球普遍存在的,增加了视神经损伤的担忧.
- 高近视与玻璃眼光神经病变共享特征,使诊断复杂化.
- 准确的区分对于管理高近视的青光眼疑似患者至关重要.
研究的目的:
- 审查和比较高近视和玻璃眼的视神经病变.
- 识别结构和功能上的相似性和差异.
- 帮助区分潜在的机制,并为管理策略提供信息.
主要方法:
- 在高近视和绿眼中对视神经病变的比较分析.
- 对 fundus 摄影发现的评估.
- 对光学连贯性断层扫描 (OCT) 的评估.
- 视觉现场测试结果的审查.
主要成果:
- 高近视和玻璃眼呈现重叠的结构和功能性视神经变化.
- 存在可以有助于差异化的特征.
- 了解这些差异是适当患者管理的关键.
结论:
- 区分高近视相关的视神经病变与青光眼之间是必不可少的.
- 使用 fundus 摄影,OCT 和视觉现场测试有助于诊断.
- 针对高近视和绿眼患者,需要量身定制的治疗策略.
相关概念视频
Glaucoma: Overview
573
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
573
Open Angle Glaucoma: Treatment
452
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
452
Photoreceptors and Visual Pathways
6.0K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.0K
Angle Closure Glaucoma: Treatment
500
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
500
Focusing of Light in the Eye
2.8K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
2.8K
Anatomy of the Eyeball
7.1K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
7.1K


