系统性免疫炎症指数与牙周炎之间的关联:一个横截面研究
Junfeng Guo1,2, Rufu Xu3, Rongxing Liu3
1Department of Pharmacy, Xinqiao Hospital, Third Military Medical University, Chongqing, China. guojfkq@163.com.
Journal of translational medicine
|January 23, 2024
概括
系统性免疫炎症指数 (SII) 与美国成年人的牙周炎有关. 患有高SII的老年人 (50+) 患有这种口腔炎症疾病的风险明显增加.
科学领域:
- 口腔健康 口腔健康
- 炎症性疾病 炎症性疾病
- 公共卫生 公共卫生
背景情况:
- 牙周炎是一种常见的慢性口腔炎症疾病,影响生活质量.
- 了解与牙周炎相关的全身标志物对于早期检测和治疗至关重要.
- 系统性免疫炎症指数 (SII) 是系统性炎症的潜在指标.
研究的目的:
- 在美国成年人群中调查系统性免疫炎症指数 (SII) 和牙周炎之间的相关性.
- 为了建立一个参考早期识别和管理策略的牙周炎.
- 分析不同年龄段SII与牙周炎的关联.
主要方法:
- 利用了来自国家牙周炎监测项目 (2009-2014) 的数据,其中包括10,366名美国成年人.
- 使用单变量和多变量加权后勤回归分析来评估SII-牙周炎相关性.
- 进行敏感性分析,以确保研究结果的可靠性.
主要成果:
- 在高SII (>978 × 10 ^ 9 / L) 和牙周炎患病率之间观察到正相关性.
- 50岁及以上的高SII的成年人显示出与牙周炎的统计学显著相关性 (OR=1.409,P=0.022).
- 在30-50岁的成年人中,在SII-牙周炎相关性中没有发现显著的统计差异.
结论:
- 系统性免疫炎症指数 (SII) 与美国成年人全国代表性样本中的牙周炎有关.
- 高SII显著与牙周炎风险增加有关,特别是在50岁及以上的人群中.
- 这些发现支持将SII作为一种潜在的生物标志物用于老年人牙周炎风险评估.
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