提高基于面板的瘤突变负担评估质量:对现实世界和in-silico结果的全面研究

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Updated: Jul 5, 2025

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
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Yuanfeng Zhang1,2,3, Duo Wang1,2,3, Zihong Zhao1,3,4

  • 1National Center for Clinical Laboratories, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Hospital/National Center of Gerontology, Beijing, PR China.

NPJ precision oncology
|January 23, 2024
PubMed
概括

标准化瘤突变负担 (TMB) 测定对免疫治疗至关重要. 本研究确定了关键的技术因素,并提供了建议,以提高基于面板的TMB测试的准确性和一致性.

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