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饮食中的活微生物和减少牙周炎的患病率:一个横截面研究
Jie Lin1, Hui Yang1, Zhengshen Lin1
1Department of Stomatology, The People's Hospital of Baoan Shenzhen, The Second Affiliated Hospital of Shenzhen University, Shenzhen, China.
Oral diseases
|January 24, 2024
概括
每天摄入中高水平的活体食微生物显著降低牙周炎的风险. 这种关联显示了剂量反应趋势,在各种人口统计和风险因素中都是如此.
科学领域:
- 微生物组研究的研究.
- 口腔健康 口腔健康
- 营养科学 营养科学
背景情况:
- 牙周炎是一种普遍存在的口腔疾病,具有重大公共卫生影响.
- 饮食因素越来越多地被认为是它们在调节慢性炎症疾病中的作用.
- 饮食中的活微生物对牙周炎风险的影响仍未得到充分研究.
研究的目的:
- 调查饮食中的活微生物消费与成人牙周炎患病率之间的关联.
- 为了确定活微生物摄入量与牙周炎风险之间是否存在剂量反应关系.
- 根据人口统计和健康行为来探索潜在的相互作用和子组差异.
主要方法:
- 利用了来自国家健康和营养检查调查 (2009-2014) 的数据,其中包括8574名成年参与者.
- 将饮食中的活微生物摄入量归类为低或中高.
- 采用回归模型,根据众多人口,生活方式和健康共变量进行调整,并进行子组分析和相互作用测试.
主要成果:
- 平均至高的每日摄入活体食微生物与牙周炎风险降低有显著关联.
- 观察到明显的剂量反应趋势 (趋势的p<0.0001).
- 在不同年龄组中发现了显著的相互作用 (p对相互作用 ≤0.05).
结论:
- 饮食中活微生物的中高消费量独立地与牙周炎风险较低有关.
- 这种保护作用是显而易见的,无论传统的风险因素和人口特征.
- 饮食中的活微生物代表了预防牙周炎的潜在可修改因素.
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