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在接受移植评估的患者中结肠多的患病率:元分析和系统性审查
Mahmoud Y Madi1, Fouad Jaber, Laith Numan
1From the Division of Gastroenterology and Hepatology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.
概括
患有慢性病的移植候选人在查结肠镜检查期间显示出结肠和腺瘤的高患病率. 这表明常规查结肠镜检查对于这个高风险群体是建议的.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
背景情况:
- 结肠直肠癌是全球癌症死亡的主要原因之一.
- 接受脏移植的人面临着显著更高的结直肠癌的风险.
- 目前对脏移植候选人的结肠直肠癌查指南与一般人群的指导方针相似.
研究的目的:
- 调查慢性病患者的结肠多的患病率,这些患者正在接受查结肠镜检查,以评估移植.
- 为了比较末期病患者与匹配的对照人群中的多和腺瘤患病率.
主要方法:
- 对2023年6月之前发表的研究进行了系统审查.
- 搜索的数据库包括PubMed,Embase和Cochrane. 这些数据库的搜索内容包括:
- 该审查重点关注了移植前慢性病患者的查结肠镜检查.
主要成果:
- 在937名患者中,有39.6%至少有一种多,有25.9%至少有一种腺瘤.
- 在8.7%的患者中发现了高风险腺瘤.
- 聚合分析显示,与对照组 (23.9%) 相比,末期病患者 (33.4%) 的腺瘤患病率较高.
结论:
- 患有慢性病的患者接受移植评估,其平均患病率为多和腺瘤多.
- 与匹配的对照组相比,末期病患者的腺瘤多的患病率更高.
- 查结肠镜对于这种人群来说是安全的,应该被认为是移植评估的常规部分.
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