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杂交的外围神经膜瘤:MRI特征与病理相关性在24例病例中

Saurabh Singh¹, Paul Choong¹, Mohamed Ali²

¹Department of Medical Imaging, Royal National Orthopaedic Hospital, London HA7 4LP, United Kingdom.

The British journal of radiology

|January 24, 2024

概括

杂交外围神经膜瘤 (HPNST) 很少显示良性瘤的典型MRI迹象. 这些瘤通常呈 lobular 形状,并可能表现出囊性变化,如本研究中详细说明的那样.

科学领域:

放射学放射学是一门学科.
在瘤学瘤学.
病理学病理学病理学

背景情况:

杂交外围神经膜瘤 (HPNST) 是一种罕见的瘤.
准确诊断HPNST对于适当的管理至关重要.
了解HPNST的特定MRI特征对于将其与其他神经膜瘤区分开来至关重要.

研究的目的:

在组织学证实混合外围神经膜瘤 (HPNST) 的磁共振成像 (MRI) 特征上划出界限.
为了确定与HPNST相关的常见和不常见的MRI发现.
将HPNST的MRI特征与通常在良性外围神经膜瘤中观察到的特征进行比较.

主要方法:

在7年的时间里,对24名经组织学证明的HPNST患者的MRI扫描进行了回顾性分析.
两个读者对MRI特征进行独立评估,包括病变形态,神经参与和特定迹象 (例如,进入/退出神经信号,目标信号).
使用科恩的卡帕系数对观察者间协议的评估.

主要成果:

这项研究包括24名患者 (9名男性,15名女性,平均年龄为50岁).
常见的MRI特征包括叶状轮 (71%) 和古/囊性变化 (38%).
很少观察到良性外围神经膜瘤的经典MRI迹象.

结论:

杂交外围神经膜瘤 (HPNST) 在MRI上经常表现出叶片形态和囊性变化.
HPNST较少显示与良性外围神经膜瘤相关的特征性MRI症状.
这项研究提供了MRI特征的第一个分析,用于组织学证明的HPNST.

关键词:

混合神经膜瘤混合神经瘤磁共振成像技术的使用神经的新生体神经.脑神经瘤的发生在神经纤维瘤中,神经纤维瘤周围神经瘤 (perineurioma) 是一个斯瓦诺马斯克人的一个问题.

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