全球纵向菌株可能是适当识别ICD植入候选人的菌株
Mohammad Hossein Nikoo1,2,3, Mohammad Zarrabi1,4, Alireza Moaref1,2
1Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Cardiology research and practice
|January 24, 2024
概括
全球纵向菌株 (GLS) 有效地识别了需要植入式心脏转换器除器 (ICD) 的高增多性心肌病 (HCM) 患者. 这种心声回声测量可以预测危及生命的心律失常,提高了ICD指示的准确性.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 心脏电生理学 心脏电生理学
背景情况:
- 超性心肌病变 (HCM) 增加了心脏突然死亡的风险.
- 植入式心脏转移器除器 (ICD) 用于初级预防.
- 目前在HCM中ICD指示的指数是不理想的.
研究的目的:
- 评估全球纵向菌株 (GLS) 作为HCM患者ICD指示的指数.
- 为了区分需要ICD冲击的HCM患者与不需要的患者.
主要方法:
- 在四个中心对34名HCM患者进行前性研究 (2021年3月至6月).
- 包括以前有ICD或当前ICD候选人的患者.
- 斑点跟踪回声心脏学测量GLS和其他参数.
- 在接受适当的ICD冲击 (心室动脉冲动/肌) 和接受不适当冲击的患者之间比较GLS.
主要成果:
- 与B组相比,在接受适当的ICD冲击 (A组) 的患者中,GLS显著更高.
- GLS是唯一一个预测致命心律失常的心声回声学参数.
- 单个单位增加的GLS与43%增加的腹腔动心率有关.
结论:
- 在HCM患者中,GLS是ICD适用于HCM患者的优异指数.
- GLS可以准确预测危及生命的心律失常,并指导适当的ICD治疗.
- 这种心声回声参数为识别高风险HCM患者提供了坚实的早期标准.
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