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瘤内在的RGS1通过ATF3-IFNGR1轴增强检查点封锁反应

Baojun Wang1,2, Bo Jiang2, Lin Du3

  • 1Department of Urology, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.

Oncoimmunology
|January 24, 2024
PubMed
概括

调节G蛋白信号传递1 (RGS1) 驱动抗瘤免疫和免疫治疗反应. 抑制RGS1导致抗PD1治疗等癌症治疗的耐药性,这表明RGS1是潜在的治疗标.

关键词:
的 IFNγ 信号传输.在NSCLCLC中,我们可以看到NSCLCLC.在 RCC RCC 里面,你会发现.一个RGS1系统.免疫疗法 免疫疗法

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