植物性饮食和心血管疾病的发病率:百万退伍军人计划
Yanping Li1,2, Dong D Wang1,3, Xuan-Mai T Nguyen1,4
1Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, Massachusetts, USA.
健康的植物性饮食显著降低了美国退伍军人的心血管疾病 (CVD) 风险. 一种不健康的植物性饮食增加了心血管疾病的风险,强调了饮食质量对退伍军人心脏健康的重要性.
科学领域:
- 心血管健康 心血管健康
- 营养流行病学 营养流行病学
- 预防医学 预防医学
背景情况:
- 植物性饮食与心脏代谢疾病有多种关联.
- 健康的植物性饮食与降低疾病风险有关,而不健康的饮食则增加了风险.
- 关于植物性饮食模式和心血管疾病 (CVD) 风险的数据有限,特别是在美国退伍军人中.
研究的目的:
- 为了研究植物性饮食模式与心血管疾病风险之间的关联,在一大群美国退伍军人中.
- 区分健康与不健康的植物性饮食模式对心血管疾病发病率的影响.
主要方法:
- 利用了148,506名退伍军人 (VA) 百万退伍军人计划中的美国退伍军人的数据,没有基线糖尿病,心血管疾病和癌症.
- 使用食物频率问卷评估饮食,计算整体植物性饮食指数 (PDI),健康的PDI (hPDI) 和不健康的PDI (uPDI).
- 在8年的随访期间,确定了CVD终点,包括非致命的心肌梗塞 (MI),急性缺血性中风 (AIS) 和致命的CVD事件.
主要成果:
- 总体PDI较高与心血管疾病风险显著降低有关 (HR比较极端五分位数=0.75).
- 较高的hPDI与心血管疾病风险有很强的反向关联 (HR=0.71),而较高的UPDI与心血管疾病风险有积极关联 (HR=1.12).
- hPDI显示,致命心血管疾病 (HR=0.81),非致命性心脏病发作 (HR=0.86) 和非致命性AIS (HR=0.86) 的风险显著降低.
结论:
- 基于植物的饮食模式,特别是那些富含更健康的植物性食品的饮食模式,与美国退伍军人的心血管疾病风险大幅降低有关.
- 强调植物性饮食模式中饮食质量对心血管健康的重要性.
- 这些发现支持在退伍军人中促进健康的植物性饮食以预防心血管疾病.
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