格雷厄姆·罗伯茨研究队列队列的一个队列概况
Beth Russell1, Poppy Leech1, Harriet Wylie1
1Translational Oncology and Urology Research, School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom.
Frontiers in oncology
|January 24, 2024
概括
格雷厄姆·罗伯茨研究是一项开创性的膀癌队列,收集有关生活质量和临床因素的数据. 未来的研究旨在开发改善膀癌预防和治疗的干预措施.
科学领域:
- 在瘤学瘤学.
- 临床试验 临床试验
- 流行病学 流行病学
背景情况:
- 格雷厄姆·罗伯茨研究于2018年启动,是第一个针对膀癌的群体内试验 (TwiCs) 研究.
- 它为膀癌患者的各种研究问题建立了基础设施.
研究的目的:
- 提供一个强大的基础设施,以回答膀癌的临床,机械和支持性护理问题.
- 促进专注于改善膀癌患者生活质量的研究.
主要方法:
- 18岁以上的同意患者,患有新发或复发的膀癌.
- 基线和年度问卷收集有关人口统计,病史,生活质量,疲劳,抑郁,健康,体力活动和饮食的数据.
- 提取临床数据,包括瘤阶段,等级和治疗.
主要成果:
- 125名膀癌患者表示同意,106人完成了基线问卷.
- 队列包括75%的新诊断和66%的非肌肉侵入性膀癌患者.
- 现有的后续数据:一年 (70),两年 (57),三年 (47),四年 (19).
结论:
- 该研究继续招募患者来扩大队列.
- 未来的研究将集中在生活质量和开发干预措施上.
- 该队列有可能改善膀癌的预防,诊断和治疗.
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